GEFITINIB INHIBITS INVASIVE PHENOTYPE AND EPITHELIAL-MESENCHYMAL TRANSITION IN DRUG-RESISTANT NSCLC CELLS WITH MET AMPLIFICATION.

Gefitinib inhibits invasive phenotype and epithelial-mesenchymal transition in drug-resistant NSCLC cells with MET amplification.

Despite the initial response, all patients with epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) eventually develop acquired KYOLIC FORMULA 104 resistance to EGFR tyrosine kinase inhibitors (TKIs).The EGFR-T790M secondary mutation is responsible for half of acquired resistance cases, while MET amplification has been

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Development of operator training support system for small-scale helicopters by automatic recovery control with attitude and velocity stabilization

Applications of small unmanned helicopters are rapidly growing in the civilian and commercial field such as pesticide spraying, aerial filming, and inspection.However, accidents often happen from deficient of operator skill, which leads to a large demand for reliable and skilled pilot.This paper describes the development of operator training suppor

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Giant Renal Artery Aneurysms: Decision-Making Dilemmas

A case of a 10 cm giant renal artery aneurysm in an 81-year-old lady is herein reported.The patient presented as an incidental finding on an abdominal ultrasound with an aneurysm which was large, soft, egg-shell-like, and bilobular with a cauliflower-type pattern invading the parenchyma of the renal substance ORG LIME JUICE and extending caudally.A

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Reconciling research and implementation in micro health insurance experiments in India: study protocol for a randomized controlled trial

Abstract Background Microinsurance or Plushie Community-Based Health Insurance is a promising healthcare financing mechanism, which is increasingly applied to aid rural poor persons in low-income countries.Robust empirical evidence on the causal relations between Community-Based Health Insurance and healthcare utilisation, financial protection and

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Hall and ion slip effects on unsteady MHD free convective rotating flow through a saturated porous medium over an exponential accelerated plate

In this paper, we have investigated the Hall and ion slip effects on the unsteady magnetohydrodynamic (MHD) free convective rotating flow over an exponentially accelerated inclined plate entrenched in a saturated porous medium with the effect of angle of inclination, variable temperature and concentration.The flow induced by the presence Alpha Lipo

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